Hybrid Aptamer-Molecularly Imprinted Polymer (AptaMIP) Nanoparticles Selective for the Antibiotic Moxifloxacin

Modified thymine bases, each containing a polymerizable group (either carboxymethylvinyl or acrylamide) at the 5-position, have been incorporated multiple times into an aptamer sequence allowing the sequence to act…

An SPR investigation toward the therapeutic drug monitoring of anticancer drug imatinib with selective aptamers operating in human plasma

The anticancer drug imatinib is often involved in therapeutic drug monitoring (TDM) studies aimed at improving the treatment of several forms of leukemia and gastrointestinal stromal tumors (GIST). To…

Literature Review: Selection, characterisation, and application of DNA aptamers for detection of Mycobacterium tuberculosis secreted protein MPT64

26th March 2019 Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains one of the main causes of human death around the globe. Mortality is high suggesting early detection and treatment would…