Can aptamers improve tests for drugs of abuse?
Drugs of abuse tests require highly selective, robust assays. Aptamers are helping to deliver new assays for more sensitive and simpler tests. According to the UN Office on Drugs…
Synthesizing new solutions for small molecule antibodies
Toni Rogers and David Bunka of Aptamer Group examine the latest tools and assays to address small molecule targets and deliver faster, cheaper and better diagnostics in this feature…
A simple displacement aptamer assay on resistive pulse sensor for small molecule detection
A universal aptamer-based sensing strategy is proposed using DNA modified nanocarriers and Resistive Pulse Sensing (RPS) for the rapid (≤20 min) and label free detection of small molecules. The surface…
Development and validation of a selective SPR aptasensor for the detection of anticancer drug irinotecan in human plasma samples
In this work, a surface plasmon resonance (SPR)-based assay for the quantification of antineoplastic drug irinotecan in human plasma samples has been developed for the first time. The selective…
Small molecule aptamer-based assay meets FDA criteria for drug monitoring
A newly published paper in The Analyst by Dr. Federico Polo, Assistant Professor at Ca’ Foscari University of Venice and former group leader at the National…
Aptamer Beacons As A Simple Solution-Based Diagnostic Platform
Molecular Aptamer Beacons are novel reagents capable of simple, solution-based detection and reporting of target concentration through a fluorescence-based readout. This assay format has a number of advantages Simple solution-based…
Rapid small molecule detection using proprietary aptamer assay
The challenge Small molecules such as antibiotics, drugs, toxins and food additives are often perceived as difficult targets to obtain a suitable affinity ligand. The development of rapid,…