Can aptamers improve tests for drugs of abuse?
Drugs of abuse tests require highly selective, robust assays. Aptamers are helping to deliver new assays for more sensitive and simpler tests. According to the UN Office on Drugs…
Hybrid Aptamer-Molecularly Imprinted Polymer (AptaMIP) Nanoparticles Selective for the Antibiotic Moxifloxacin
Modified thymine bases, each containing a polymerizable group (either carboxymethylvinyl or acrylamide) at the 5-position, have been incorporated multiple times into an aptamer sequence allowing the sequence to act…
New methods for hapten bioanalysis
Anti-hapten antibodies are difficult and slow to generate limiting cheap and efficient bioanalysis in this field. Our proprietary methods offer standard assay formats, such as ELISA and lateral flow…
QSM Diagnostics: Spying on bacteria for rapid diagnostic applications
Novel diagnostic platforms are bringing possibilities for improved patient care and reduced healthcare costs. We spoke with Dr Edgar Goluch, the CEO and founder of QSM Diagnostics,
Development and validation of a selective SPR aptasensor for the detection of anticancer drug irinotecan in human plasma samples
In this work, a surface plasmon resonance (SPR)-based assay for the quantification of antineoplastic drug irinotecan in human plasma samples has been developed for the first time. The selective…
An SPR investigation toward the therapeutic drug monitoring of anticancer drug imatinib with selective aptamers operating in human plasma
The anticancer drug imatinib is often involved in therapeutic drug monitoring (TDM) studies aimed at improving the treatment of several forms of leukemia and gastrointestinal stromal tumors (GIST). To…
Biomarker detection in serum made easier with aptamer-based biosensors
Blood contains a range of protein biomarkers that could be used in the early detection of disease. One important biomarker is human epidermal growth factor receptor 2 (HER2) which…