Aptamers for siRNA delivery
15th May 2019 siRNA’s are functional double stranded RNA molecules which can be used to control gene expression by targeting a messenger RNA and promoting its degradation. One…
15th May 2019 siRNA’s are functional double stranded RNA molecules which can be used to control gene expression by targeting a messenger RNA and promoting its degradation. One…
7th May 2019 Glycosylation is a post-translational modification where a carbohydrate is added to a protein. Glycosylation of proteins serves a number of functions in a cell, including: improve…
23rd April 2019 We have often shown that aptamers make ideal ‘capture reagents’ for use in target specific affinity chromatography. Their flexible structure makes aptamers ideally suited for…
2nd April 2019 Background: Post Translational Modifications (PTM) are biochemical variations of certain amino acids made to a protein after biosynthesis. These modifications diversify the proteome and play a…
26th March 2019 Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains one of the main causes of human death around the globe. Mortality is high suggesting early detection and treatment would…
19th March 2019 Breast cancer is a highly heterogeneous tumour conventionally classified into four molecular subtypes, i.e., Luminal A, Luminal B, HER2-enriched, and triple-negative breast cancer. In clinical practice…
15th January 2019 Aptamers have a great potential in cancer biomarker discovery via selection against cancer cells following counter selection against healthy cells. Aptamers were identified to bind to cancer…
19th December 2018 This month: Aptamer Group data on selective cell based biomarker aptamers The year in review, from new product launches to company accolades Interesting applications in international…
3rd December 2018 Aptamer Group is proud to receive the CEO Today Magazine United Kingdom Awards for distinguished performance by our CEO and Founder Arron Tolley. The…
29th November 2018 This month: Aptamer Group data on selective bind and elution reusability of aptamer purification columns Small molecule analysis webinar with Pall ForteBio BLI platform Our CEO…