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Performance analysis of SARS-CoV-2 Optimer reagents to evolving viral variants

As part of the COVID-19 pandemic Optimer reagents were developed to the SARS-CoV-2 viral S protein. Ongoing mutations seen in SARS-CoV-2 have resulted in the emergence of variant strains with significant mutations in the S protein. To ensure accurate research and diagnostics all tests should recognize the WT and variant strains of SARS-CoV-2. In this study. the binding and affinity of the SARS-CoV-2 Optimer reagents were characterized for the S protein WHO designated variants of concern and irradiated virus of SARS-CoV-2 variants.

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