Antibiotic resistance is increasing globally and represents one of the biggest public health challenges of our time. In the US alone, there are more than 2.8 million cases of…

Why are haptens such a hard-to-solve target class for antibody development? Small molecules are ubiquitous in our environment. They cover hormones and toxins to drugs and vitamins. There is an…

Researchers at the National Cancer Institute (Centro di Referimento Oncologico IRCCS), Aviano, Italy, have published a new paper in Analytical and Bioanalytical Chemistry. Using aptamers from Aptamer…

In the recently published paper in Talenta from Dr Mark Platt and the team at Loughborough University, they demonstrate a novel approach for aptamer biosensors to detect…

A newly published paper in The Analyst by Dr. Federico Polo, Assistant Professor at Ca’ Foscari University of Venice and former group leader at the National…

SARS-CoV-2 was first identified in November 2019 in Wuhan, China. Spreading quickly across the globe, COVID-19, the disease caused by SARS_CoV-2, was announced as a pandemic just four months…

Blood contains a range of protein biomarkers that could be used in the early detection of disease. One important biomarker is human epidermal growth factor receptor 2 (HER2) which…

Proteins can undergo post-translational modification (PTM) of their amino acids which can lead to a change in their activity and increase their functional repertoire. The most common of these…

The challenge Small molecules such as antibiotics, drugs, toxins and food additives are often perceived as difficult targets to obtain a suitable affinity ligand. The development of rapid,…

Biomarker Discovery A biomarker is a measurable indicator showing the presence or severity of a disease state. Using biomarkers to differentiate between healthy and diseased cells can enable…