Applications of aptamers as GPCR targeting drugs
The current wave of COVID-19 infections around the globe has resulted from a novel coronavirus employing its spike glycoprotein to bind with the protein binding sites of the host…
The current wave of COVID-19 infections around the globe has resulted from a novel coronavirus employing its spike glycoprotein to bind with the protein binding sites of the host…
Purification of functional proteins is a key procedure in the development and production of biologics and relies on traditional ion exchange (IEX), hydrophobic interaction (HIC) or size exclusion chromatography…
DNA–protein interactions constitute essential biological processes such as replication, transcription and DNA repair. Mechanistic knowledge of these interactions offers insight into cell regulation, which holds the key to unlocking…
The contamination of the environment with pesticide residues has become one of the most serious problems of public health in the world, due to their wide application in agriculture…
Aptamer based ‘gain-of-signal’ assay for small molecule detection Detecting small molecules represents a challenge for In vitro diagnostics (IVD) due to the sensitivity and specificity limits of many detection methods….
Small molecules present an ongoing challenge for antibody production and detection. Development of biosensors for the detection of small molecules is difficult due to the lack of suitable antibodies…
Molecular Aptamer Beacons are novel reagents capable of simple, solution-based detection and reporting of target concentration through a fluorescence-based readout. This assay format has a number of advantages Simple solution-based…