Cystic fibrosis (CF) is one of the most lethal autosomal recessive disorder caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). It is estimated that…

Aptamer mediated Hot start PCR to detect MERS-CoV Polymerase chain reaction (PCR) is an established method to amplify specific fragments of DNA, for applications such as…

Cancer histopathology is currently the preferred method for detecting microscopic anatomical changes in tissue sections, making the discovery of cancer biomarkers critical for early diagnosis and treatment. Antibodies have…

Benefits of Aptamers for Protein Applications Proteins play significant roles in the physiological and pathological mechanisms of living organisms including human beings. There is an increased demand for convenient methodologies…

Infectious diseases are among the common leading causes of morbidity and mortality worldwide. Let’s take an example of the current scenario where the world is gripped by the novel…

Antibiotics have been widely used in human medicine, aquaculture and agriculture to treat serious infectious diseases. However, overuse and misuse of antibiotics in some areas have contributed to the…

Immunohistochemistry has helped to make surgical pathology the ‘gold standard’ for tumour diagnosis. Antibodies have been used extensively as molecular probes; however, there have been issues with their specificity,…

The challenge Small molecules such as antibiotics, drugs, toxins and food additives are often perceived as difficult targets to obtain a suitable affinity ligand. The development of rapid,…

Biomarker Discovery A biomarker is a measurable indicator showing the presence or severity of a disease state. Using biomarkers to differentiate between healthy and diseased cells can enable…

Drug abuse continues to be a growing global concern, causing serious health and economic implications worldwide. These drugs are known to be a strong stimulant to the central nervous…