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Cell specific staining

Cell specific staining in Confocal Imaging Over the next few weeks we are going to look at examples of where we have developed aptamers for cell imaging. One of…

Aptamer Application: Biomarker Discovery

A biomarker is a measurable indicator showing the presence or severity of a disease state. Using biomarkers to differentiate between healthy and diseased cells can enable the development of…

Aptamer Application: Flow Cytometry

Flow Cytometry Flow Cytometry is a technique used to identify biomarkers on cell surfaces and intracellular molecules. Most flow cytometers use fluorescently labelled antibodies to differentiate between cells…

Aptamer Applications: Western Blotting

AptaBlot – increasing the utility of Western Blotting Western Blotting is a powerful technique used to detect and identify proteins. Antibodies have traditionally been used as the detection…

AptaBasics: Aptamer Affinity

Aptamer Affinity Aptamers are affinity reagents, so the mechanism of binding to a target is a key characteristic. Today we discuss how aptamers bind and outline what we…

Aptamer Applications: Biosensors part 2

Here we outline two strategies for utilising aptamers in biosensors. Target Induced Displacement Mode Target Induced Displacement (TID) mode uses an aptamer anchored via a complementary oligo,…